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1177. Functional chimeric mRNAs encode proteins in mammalian immunity

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10982-xInflammation induces interchromosomal DNA interactions that bring parent genes into close proximity, facilitating the formation of chimeric mRNAs that encode physiologically relevant, functional proteins.

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1178. Audio long read: Could mending damaged DNA prolong life?

Nature, Published online: 02 September 2026; doi:10.1038/d41586-026-02762-4Researchers are hunting for ways to enhance DNA repair with the hopes that this will keep people healthier for longer.

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1179. Structure and operating principles of a monkeypox virus replisome

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10937-2During replisome assembly of monkeypox virus, the hexameric helicase–primase E5 undergoes large-scale conformational changes that allow two of its primase domains to interact with the polymerase F8 thumb domain and A22 subunit, activating the helicase–primase.

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1180. Intracellular complement factor H protects neurons during CNS inflammation

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10981-yCFH is a key mediator of neuronal resilience across the central nervous system in mice and humans.

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1181. Probing far-from-equilibrium dynamics of electrical double layers

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10986-7A new framework combining experimental and computational methods to track ions and water present at an electrode interface allows the molecular structure and evolution of electrical double layers far from equilibrium to be discovered.

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1182. The nutritional value of invertebrate aquatic foods

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10908-7Aquatic invertebrates are exceptionally nutrient dense, supplying the equivalent annual vitamin B12 and selenium requirements for over 5 billion people.

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1183. Current therapeutic landscape and future treatment perspectives of MASH

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10672-8The therapeutic landscape and advances in biomarkers for metabolic dysfunction-associated steatohepatitis are reviewed.

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1184. Explainable deep learning improves human mental models of self-driving cars

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10950-5Concept-Wrapper Network, a concept-based explanation approach deployed on a real autonomous vehicle, improves drivers’ ability to understand and predict its behaviour.

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1185. Molecular mechanisms and pathogenesis of MASH

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10529-0This Review highlights the state of the art of molecular and cellular mechanisms underlying MASH pathogenesis and its transition to hepatocellular carcinoma.

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1186. Rewiring the ribosome to translate proteins encoded in its own RNA

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10962-1Bacterial ribosomes can synthesize proteins encoded within their own RNA.

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1187. Atmospheric CH4 plateau sustained by NOx emission rise and southward shift

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10983-wThe atmospheric methane plateau can be explained by tropical hydroxyl radical enhancement primarily driven by a global rise and spatial redistribution of nitrogen oxides emissions towards developing regions and the oceans.

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1188. Pines grow faster and are more drought resilient in the Southern Hemisphere

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10969-8Non-native conifers from the Northern Hemisphere grow faster and are more drought resistant and resilient in the Southern Hemisphere, where they seem to escape the growth–stress-tolerance trade-off.

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1189. Exploring baryon semileptonic decays through polarization and entanglement

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10818-8Polarization and quantum entanglement measurements of baryon semileptonic decay greatly enhance single-event sensitivity, and combined with lattice quantum chromodynamics calculations enable determination of the |Vus| element of the Cabibbo–Kobayashi–Maskawa matrix, providing an independent test of the standard model.

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1190. Robust inference and correlates from genetic associations with personality

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10992-9The genetic architecture of personality is robustly generalizable, minimally confounded and widely relevant to human experience.

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1191. Late-life semaglutide treatment slows ageing and extends lifespan in female mice

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10940-7Semaglutide treatment for 3 months in female mice improved physiological function, attenuated hallmarks of ageing and modulated nutrient sensors and conserved genetic regulators of ageing.

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1192. Creating bottom-up RNA transfer vehicles from synthetic protein assemblies

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10952-3Synthetic virus-like protein architectures designed by artificial intelligence show superior ability to deliver RNA into cells, compared with their naturally occurring counterparts, by overcoming the evolutionary constraints limiting viral evolution.

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1193. Designing physics experiments with artificial intelligence

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10898-6Artificial intelligence in physics experimental design is explored on the basis of searching for optima over a vast space of hardware configurations and proposing entirely new experimental layouts, rather than tuning a handful of parameters.

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1194. Connectome analysis of a cerebellum-like circuit for sensory prediction

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10690-6Connectomics, electrophysiology and modelling of electric fish neural circuits shows how distributed synaptic plasticity across multiple network layers cooperates to enable fast, accurate and noise-robust sensory learning.

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1195. 3D epigenome of glial cell types in developing human cortex

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10987-6Integrative 3D epigenomic profiling of four glial cell types from the mid-gestation human cortex reveals cell-type-specific regulatory elements and chromatin interactions that illuminate the roles of non-coding variants in neuropsychiatric disease and human-specific cortical evolution.

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1196. Retraction Note: Warming accelerates global drought severity

Bản tin từ Nature Science. Vui lòng bấm vào link để đọc toàn văn.

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1197. Author Correction: Endocannabinoids facilitate reward engagement through retrograde gain control

Bản tin từ Nature Science. Vui lòng bấm vào link để đọc toàn văn.

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1198. Alzheimer’s may leave a mark on the brain long before plaques appear

Brain changes associated with Alzheimer’s may begin at least seven years before amyloid plaques become detectable with current PET scans. Researchers uncovered the signal by tracking healthy older adults with repeated brain imaging over nearly 20 years. The discovery could help scientists identify Alzheimer’s earlier and suggests that important disease processes may start before visible plaque buildup.

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1199. Money problems may age your brain faster

Persistent financial hardship in early and middle adulthood was linked to poorer thinking skills by the 50s and more signs of brain aging later in life. Researchers say years of chronic stress and financial worry may gradually take a toll on the brain.

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1200. Interstellar solar sails hit a strange problem at 75% of light speed

Solar sails pushed by powerful lasers could reach incredible speeds, but relativity may eventually make the light itself work against them. At around 75% of the speed of light, scattered photons can begin creating drag, adding a surprising obstacle to interstellar travel.

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