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2593. Rational design of disordered proteins for sequence–function investigation

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10849-1GOOSE enables the design and testing of thousands of disordered protein region sequences to reveal distinct sequence-to-function relationships.

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2594. A global view of human centromere variation and evolution

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10841-9Complete sequencing of more than 2,000 centromeres from diverse humans reveals structures and elevated mutation rates that shape the evolution of these critically important regions.

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2595. A digitally controlled silicon quantum processing unit

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10754-7A silicon quantum processing unit executes high-fidelity multiqubit circuits, with all time-varying control signals generated by a digitally programmed cryogenic complementary metal–oxide–semiconductor controller and delivered to the low-noise, exchange-only qubit device through a high-density superconducting ribbon cable.

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2596. Enzymatic glycosylation and amidation reshapes polyene bioactivity

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10834-8Pathways to previously undescribed polyenes, including unusual enzymes that introduce more sugars onto polyene scaffolds, are discovered, and their accessibility through clean and efficient fermentation and potential for safe use as antifungal treatments is described.

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2597. Weight-four parity checks in a spin-shuttling architecture

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10766-3A silicon spin-qubit device comprising a shuttling bus for transporting qubits is used to achieve parity checks up to weight four, highlighting the feasibility and benefits of incorporating shuttling into semiconductor quantum processors.

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2598. New-deal mortgage programmes benefited white borrowers disproportionately

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10850-8New data on homebuying loan records around the Second World War in the USA, linked to race and immigration status, show that Black borrowers were disproportionally excluded from mortgage programmes.

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2599. Perpendicular switching of polarization in layered ferroelectrics

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10839-3Perpendicular switching of the polarization state in the layered ferroelectric Bi4Ti3O12 is demonstrated by means of trilinear coupling, allowing manipulation of the in-plane polarization component with an out-of-plane electric field.

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2600. Sequential reading of a stepwise-shortened peptide immobilized on nanopore

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10881-1A nanopore-based ‘chop and measure’ method sequences peptides at single-amino-acid resolution by using enzymatic digestion to progressively shorten the N terminus one residue at a time, together with repetitive N-terminus re-reading.

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2601. Avalanche-like intercalation and intraparticle correlations in graphite

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10862-4Operando optical microscopy shows avalanche-like lithium deintercalation (intercalation) processes as the dilute stages of graphite are emptied (filled), showing how local disorder governs phase-transition dynamics and ion transport in lithium-ion battery electrodes.

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2602. Alternating CO2 and bicycloalkane copolymerization to circular polyesters

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10848-2A simple organic catalyst enables direct alternating copolymerization of CO2 with bicycloalkanes to produce high-performance polyesters that can be selectively depolymerized and recycled in a closed-loop lifecycle.

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2603. Mitochondrial metabolism and epigenetic crosstalk drive SASP

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10791-2In senescent cells, mitochondria-derived acetyl-CoA promotes histone acetylation and increases chromatin accessibility at inflammatory gene loci. Inhibition of SLC25A1 attenuates these effects, underscoring the therapeutic potential of targeting mitochondrial metabolism and its epigenetic crosstalk to delay age-related functional decline.

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2604. Diverse bacterial pattern recognition receptors sense the core phage proteome

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10852-6Systematic analysis of prokaryotic STAND NTPases — relatives of animal and plant immune receptors — uncovers diverse antiviral sensors that detect most of the core structural and replicative proteins of bacteriophages.

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2605. The piezochiral effect

Bản tin từ Nature Science. Vui lòng bấm vào link để đọc toàn văn.

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2606. Earthworks spotted in the Amazon hint at huge ancient civilization

Nature, Published online: 29 July 2026; doi:10.1038/d41586-026-02367-xDiscovery of almost 400 structures may help to redefine the true scale of the Aquiry civilization — plus, tiny fossils of the earliest fossil squid ancestor.

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NGHIÊN CỨU Wed, 29 Ju

2607. NCS. Nguyễn Quốc Tùng bảo vệ thành công Luận án tiến sĩ tại Hội đồng bảo vệ Học viện Tài chính

Bản tin từ Học viện Tài chính. Vui lòng bấm vào link để đọc toàn văn.

Học viện Tài chính Tích cực

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2608. The dark horse of biology: how RNA is becoming a nanotool maker’s dream

Nature, Published online: 29 July 2026; doi:10.1038/d41586-026-02180-6Scientists are harnessing its ability to fold, switch and reorganize itself to create a new generation of cellular technologies.

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2609. To help children with rare diseases, we must solve drug delivery

Nature, Published online: 29 July 2026; doi:10.1038/d41586-026-02182-4Nanoparticle technologies hold promise for delivering gene therapies to children with few treatment options.

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2610. How mosquitoes are conquering the world — in four charts

Nature, Published online: 29 July 2026; doi:10.1038/d41586-025-03966-wMosquito-borne diseases are breaking records as climate change and other human influences allow the insects to expand their range.

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2611. Three rising stars of nanoscience and nanotechnology

Nature, Published online: 29 July 2026; doi:10.1038/d41586-026-02181-5The smallest building blocks are enabling next-generation solutions.

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2612. A guide to the Nature Index

Nature, Published online: 29 July 2026; doi:10.1038/d41586-026-02183-3A description of the terminology and methodology used in this supplement, and a guide to the functionality that is available free online at natureindex.com.

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2613. Was art key to ancient humans' success? The secrets of Hohle Fels cave

Nature, Published online: 29 July 2026; doi:10.1038/d41586-026-02359-xNew discoveries at famous archeological site add to mystery of ancient human culture.

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2614. Why tomorrow’s nanotechnologies need support today

Nature, Published online: 29 July 2026; doi:10.1038/d41586-026-02179-zThe field seems to be on the cusp of big advances, but a concerted effort is needed to realize its true potential.

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2615. Author Correction: A ductile solid electrolyte interphase for solid-state batteries

Bản tin từ Nature Science. Vui lòng bấm vào link để đọc toàn văn.

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NGHIÊN CỨU Tue, 28 Ju

2616. 4 in 5 toddler foods are ultra-processed

A grocery-store audit found that many foods marketed for toddlers may be far less healthy than parents expect. Of nearly 2,800 products examined in Texas, 81% were ultra-processed, and almost half failed at least one World Health Organization nutrient standard, often because they contained too much sugar, sodium, fat, or too many calories.

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